Critical Knowledge Gaps in Mass Transport through Single-Digit Nanopores: A Review and Perspective


Journal of Physical Chemistry C 2019, 123, 35, 21309-21326

Samuel Faucher, Narayana Aluru, Martin Z. Bazant, Daniel Blankschtein, Alexandra H. Brozena, John Cumings, J. Pedro de Souza, Menachem Elimelech, Razi Epsztein, John T. Fourkas, Ananth Govind Rajan, Heather J. Kulik, Amir Levy, Arun Majumdar, Charles Martin, Michael McEldrew, Rahul Prasanna Misra, Aleksandr Noy, Tuan Anh Pham, Mark Reed, Eric Schwegler, Zuzanna Siwy, YuHuang Wang, and Michael Strano


The abstract reads as follows: Not all nanopores are created equal. By definition, nanopores have characteristic diameters or conduit widths between ∼1 and 100 nm. However, the narrowest of such pores, perhaps best called Single Digit Nanopores (SDNs) and defined as those with regular diameters less than 10 nm, have only recently been accessible experimentally for precision transport measurements. This Review summarizes recent experiments on pores in this size range that yield surprising results, pointing toward extraordinary transport efficiencies and selectivities for SDN systems. These studies have identified critical gaps in our understanding of nanoscale hydrodynamics, molecular sieving, fluidic structure, and thermodynamics. These knowledge gaps are, in turn, an opportunity to discover and understand fundamentally new mechanisms of molecular and ionic transport at the nanometer scale that may inspire a host of new technologies, from novel membranes for separations and water purification to new gas-permeable materials and energy storage devices. Here we highlight seven critical knowledge gaps in the study of SDNs and identify the need for new approaches to address these topics.

This work and all authors were supported as part of the Center for Enhanced Nanofluidic Transport, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award No. DESC0019112.